Cardiovascular Pathology
Volume 9, Issue 1 , Pages 53-54, January 2000

Severe Heart Valve Calcification in a Young Patient with Werner Syndrome☆

  • Herko Grubitzsch, MD

      Affiliations

    • Clinic for Cardiothoracic and Vascular Surgery, Heart and Diabetes Centre Mecklenburg-Vorpommern, Klinikum Karlsburg, Germany
    • Corresponding Author InformationAddress for correspondence: Dr. H. Grubitzsch, Klinik für Herz-, Thorax- und Gefäßchirurgie, Herz- und Diabetes-Zentrum Mecklenburg-Vorpommern, Klinikum Karlsburg, Greifswalder Str. 11 A, D-17495 Karlsburg, Germany; Tel.: 004938355/701330; Fax: 004938355/701577,
    • ,
  • Sven Beholz, MD

      Affiliations

    • Clinic for Cardiothoracic and Vascular Surgery, Heart and Diabetes Centre Mecklenburg-Vorpommern, Klinikum Karlsburg, Germany
    • ,
  • Hans-Georg Wollert, MD

      Affiliations

    • Clinic for Cardiothoracic and Vascular Surgery, Heart and Diabetes Centre Mecklenburg-Vorpommern, Klinikum Karlsburg, Germany
    • ,
  • Lothar Eckel, MD

      Affiliations

    • Clinic for Cardiothoracic and Vascular Surgery, Heart and Diabetes Centre Mecklenburg-Vorpommern, Klinikum Karlsburg, Germany

Received 21 July 1999; received in revised form 11 October 1999; accepted 11 November 1999.

Abstract 

Werner syndrome is a rare autosomal recessive disorder characterized by the appearance of premature aging. We report on severe aortic and mitral valve calcification in an 18-year-old girl, necessitating double valve replacement. These special cardiovascular findings are discussed with regard to diagnosis and treatment.

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☆ Present affiliation for Dr. Beholz: Clinic for Cardiac Surgery, Humboldt University, Charité, Berlin, Germany.

PII: S1054-8807(99)00036-8

Cardiovascular Pathology
Volume 9, Issue 1 , Pages 53-54, January 2000

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