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Deletion of tenascin-C gene exacerbates atherosclerosis and induces intraplaque hemorrhage in Apo-E-deficient mice

  • Lai Wang

      Affiliations

    • Oppenheimer Atherosclerosis Research Center and the Division of Cardiology, Cedars Sinai Heart Institute, Los Angeles, CA 90048, USA
    • ,
  • Wei Wang

      Affiliations

    • Department of Animal and Veterinary Sciences, College of Agriculture, California State Polytechnic University, Pomona, 91768, USA
    • ,
  • Prediman K. Shah

      Affiliations

    • Oppenheimer Atherosclerosis Research Center and the Division of Cardiology, Cedars Sinai Heart Institute, Los Angeles, CA 90048, USA
    • ,
  • Lei Song

      Affiliations

    • Oppenheimer Atherosclerosis Research Center and the Division of Cardiology, Cedars Sinai Heart Institute, Los Angeles, CA 90048, USA
    • ,
  • Mingjie Yang

      Affiliations

    • Oppenheimer Atherosclerosis Research Center and the Division of Cardiology, Cedars Sinai Heart Institute, Los Angeles, CA 90048, USA
    • ,
  • Behrooz G. Sharifi

      Affiliations

    • Oppenheimer Atherosclerosis Research Center and the Division of Cardiology, Cedars Sinai Heart Institute, Los Angeles, CA 90048, USA
    • Corresponding Author InformationCorresponding author. Oppenheimer Atherosclerosis Research Center, Division of Cardiology, Cedars-Sinai Medical Center, Davis Bldg. #1016, 8700 Beverly Blvd., Los Angeles, CA 90048. Tel.: +1 310 423 7621; fax: +1 310 423 0922.

Received 26 October 2011 ,Revised 13 December 2011 ,Accepted 17 December 2011. Published online 02 February 2012 Corrected Proof

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 This work was supported by grants from the National Institutes of Health (ROI HL50566), The Eisner Foundation, The Heart Foundation, Spielberg Cardiovascular Research Fund, the Corday Foundation, Sam Spaulding Fund, and The California Agricultural Research Initiative (grant # 03-4-089). B.G.S. is an established investigator of the American Heart Association.

PII: S1054-8807(11)00157-8

doi: 10.1016/j.carpath.2011.12.005

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