Cardiovascular Pathology
Volume 20, Issue 5 , Pages 315-321 , September 2011

Clear cells in the atrioventricular valves of infants with severe human mucopolysaccharidosis (Hurler syndrome) are activated valvular interstitial cells

  • Elizabeth Braunlin

      Affiliations

    • Department of Pediatrics, University of Minnesota Hospital/Fairview, Minneapolis, MN, USA
    • Corresponding Author InformationCorresponding author. Department of Pediatrics, University of Minnesota Hospital/Fairview, MMC 94, Minneapolis, MN 55455, USA. Tel.: +1 612 626 2755; fax: +1 612 626 2467.
    • ,
  • Jakub Tolar

      Affiliations

    • Department of Pediatrics, University of Minnesota Hospital/Fairview, Minneapolis, MN, USA
    • ,
  • Shannon Mackey-Bojack

      Affiliations

    • The Jesse E. Edwards Registry of Cardiovascular Disease, St. Paul, MN, USA
    • ,
  • Tiwanda Masinde

      Affiliations

    • Cellular and Molecular Pathology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
    • ,
  • William Krivit

      Affiliations

    • Department of Pediatrics, University of Minnesota Hospital/Fairview, Minneapolis, MN, USA
    • Deceased.
    • ,
  • Frederick J. Schoen

      Affiliations

    • Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA

Received 18 February 2010 ,Revised 6 May 2010 ,Accepted 2 June 2010.

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 This work was supported by a grant from the Vikings Fund at the University of Minnesota Medical Foundation.

 Elizabeth Braunlin, MD, PhD receives speaker’s honoraria from Genzyme and Biomarin companies, both of which produce an enzyme treatment for MPS I.

 Jakub Tolar, MD, PhD receives speaker’s honoraria from Genzyme company.

PII: S1054-8807(10)00076-1

doi: 10.1016/j.carpath.2010.06.004

Cardiovascular Pathology
Volume 20, Issue 5 , Pages 315-321 , September 2011

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