Cardiovascular Pathology
Volume 20, Issue 3 , Pages 156-161 , May 2011

Association between AT C573T polymorphism and cardiovascular risk factors in myocardial infarction

  • Maria M. Morales-Suarez-Varela

      Affiliations

    • Unit of Public Health and Environmental Care, Department of Preventive Medicine and Public Health, University of Valencia, Valencia, Spain
    • Research Foundation, Dr. Peset University Hospital, Valencia, Spain
    • CIBER Epidemiology and Public Health (CIBERESP), Spain
    • Corresponding Author InformationCorresponding author. Unit of Public Health and Environmental Care, Department of Preventive Medicine, University of Valencia, Avda. Vicente Andrés Estellés s/n, 46100 Burjasot, Valencia, Spain. Tel.: +34 96 3544951; fax: +34 96 3544951.
  • ,
  • Concepción Riera-Fortuny

      Affiliations

    • Xirivella Health Centre, Valencia, Spain
  • ,
  • Maria-Luisa Mansego

      Affiliations

    • CIBER Physiopathology of Obesity and Nutrition, Spain
    • Genotyping and Genetic Diagnosis Unit, Hospital Clinico Research Foundation and INCLIVA, University of Valencia, Valencia, Spain
  • ,
  • Maria-Luisa Martinez-Triguero

      Affiliations

    • Unit of Clinical Analysis, University Hospital La Fe, Valencia, Spain
  • ,
  • Felipe-Javier Chaves

      Affiliations

    • Genotyping and Genetic Diagnosis Unit, Hospital Clinico Research Foundation and INCLIVA, University of Valencia, Valencia, Spain
    • CIBER Diabetes and Associated Metabolic Diseases, Barcelona, Spain
  • ,
  • Jose M. Martin-Moreno

      Affiliations

    • Unit of Public Health and Environmental Care, Department of Preventive Medicine and Public Health, University of Valencia, Valencia, Spain
    • Quality Unit, University Clinical Hospital, Valencia, Spain
  • ,
  • Celia Bañuls

      Affiliations

    • CIBER Epidemiology and Public Health (CIBERESP), Spain
    • Endocrinology Service, Dr. Peset University Hospital, Valencia, Spain
  • ,
  • Antonio Hernandez-Mijares

      Affiliations

    • CIBER Epidemiology and Public Health (CIBERESP), Spain
    • Endocrinology Service, Dr. Peset University Hospital, Valencia, Spain
    • Department of Medicine, School of Medicine, University of Valencia, Valencia, Spain

Received 2 November 2009 ,Revised 15 March 2010 ,Accepted 12 April 2010.

References 

  1. Hernández-Mijares A, Riera-Fortuny C, Solà-Izquierdo E, Oliver Oliver MJ, Martínez-Triguero ML, Morillas Ariño C, et al. Prevalence of metabolic syndrome in patients with coronary heart disease. Med Clin. 2003;121(6):204–208
  2. Bennet AM, Di Angelantonio E, Ye Z, Wensley F, Dahlin A, Ahlbom A, et al. Association of apolipoprotein E genotypes with lipid levels and coronary risk. JAMA. 2007;298:1300–1311
  3. Domingues-Montanari S, Subirana I, Tomás M, Marrugat J, Sentí M. Association between ESR2 genetic variants and risk of myocardial infarction. Clin Chem. 2008;54(7):1183–1189
  4. Halder I, Muldoon MF, Ferrell RE, Manuck SB. Serotonin receptor 2A (HTR2A) gene polymorphisms are associated with blood pressure, central adiposity, and the metabolic syndrome. Metab Syndr Relat Disord. 2007;5(4):323–330
  5. Järemo P, Nilsson O. Interleukin-6 and neutrophils are associated with long-term survival after acute myocardial infarction. Eur J Intern Med. 2008;19(5):330–333
  6. Khan SQ, Dhillon O, Kelly D, Squire IB, Struck J, Quinn P, et al. Plasma N-terminal B-type natriuretic peptide as an indicator of long-term survival after acute myocardial infarction: comparison with plasma midregional pro-atrial natriuretic peptide: the LAMP. J Am Coll Cardiol. 2008;51(19):1857–1864
  7. Chaves FJ, Pascual JM, Rovira E, Armengod ME, Redon J. Angiotensin II AT1 receptor gene polymorphism and microalbuminuria in essential hypertension. Am J Hypertens. 2001;14:364–370
  8. Tiago AD, Bandenhorst D, Nkeh B, Candy GP, Brooksbank R, Sareli P, et al. Impact of renin–angiotensin–aldosterone system gene variants on the severity of hypertension in patients with newly diagnosed hypertension. Am J Med Sci. 2004;328(5):266–273
  9. Galderisi M, Divitiis OD. Risk factor-induced cardiovascular remodeling and the effects of angiotensin-converting enzyme inhibitors. J Cardiovasc Pharmacol. 2008;51(6):523–531
  10. Strazzullo P, Iacone R, Iacovello L, Russo O, Barba G, Russo P, et al. Genetic variation in the renin–angiotensin system and abdominal adiposity in men: the Olivetti Prospective Heart Study. Intern Med. 2003;138(1):17–23
  11. Riera-Fortuny C, Real JT, Chaves FJ, Morales-Suarez-Varela M, Martínez-Triguero ML, Morillas Ariño C, et al. The relation between obesity, abdominal fat deposit and the angiotensin-converting enzyme gene I/D polymorphism and its association with coronary heart disease. Int J Obes (Lond). 2005;29(1):78–84
  12. Staessen J, Wang JG, Ginocchio G, Petrov V, Saavedra A, Soubrier F, et al. The deletion/insertion polymorphism of the angiotensin converting enzyme gene and the cardiovascular–renal risk. J Hypertens. 1997;15:1379–1592
  13. Su S, Chen J, Zhao J, Huang J, Wang X, Chen R, et al. Angiotensin II type 1 receptor gene and myocardial infarction: tagging SNPs and haplotype based association study: the Beijing Atherosclerosis Study. Pharmacogenetics. 2004;14:673–681
  14. Araujo MA, Goulart LR, Codeiro ER, Gatti RR, Menezes BS, Lourenço C, et al. Genotypic interactions of renin–angiotensin system genes in myocardial infarction. Int J Cardiol. 2005;103:27–32
  15. Rodríguez-Pérez JC, Rodríguez-Esparragón F, Hernández-Perera O, Anabitarte A, Losada A, Medina A, et al. Association of angiotensinogen M235T and A(-6) G gene polymorphism with coronary heart disease with independence of essential hypertension: the PROCAGENE study (Prospective Cardiac Gene). J Am Coll Cardiol. 2001;37(6):1536–1542
  16. Andrikopoulos GK, Tzeis SM, Neddham EW, Richter DJ, Zairis MN, Gialafos EJ, et al. Lack of association between common polymorphisms in genes of the renin–angiotensin system and mortality after myocardial infarction. Cardiology. 2005;103:185–188
  17. Franco E, Palumbo L, Crobu F, Anselmino M, Frea S, Matullo G, et al. Renin–angiotensin–aldosterone system polymorphisms: a role or a hole in occurrence and long-term prognosis of acute myocardial infarction at young age. BMC Med Genet. 2007;8:27
  18. Zhu TN, Pan JQ, Shen ZJ, Zhao YQ, Shen T. Gene polymorphisms of renin–angiotensin system and coronary artery thrombosis disease. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2004;12(5):674–679
  19. Sekuri C, Cam FS, Ercan E, Tengiz I, Sagcan A, Eser E, et al. Renin–angiotensin system gene polymorphisms and the premature coronary heart disease. J Renin Angiotensin Aldosterone Syst. 2005;6(1):38–42
  20. Andrikopoulos GK, Richter DJ, Needham EW, Tzeis SE, Zairis MN, Gialafos EJ, et al. The paradoxical association of common polymorphisms of the renin–angiotensin system genes with risk of myocardial infarction. Eur J Cardiovasc Prev Rehabil. 2004;11(6):477–483
  21. Lao O, Dupanloup I, Barbujani G, Bertranpetit J, Calafell F. The Mediterranean paradox for susceptibility factors in coronary heart disease extends to genetics. Ann Hum Genet. 2008;72(pt1):48–56
  22. Rijn MJ, Boss MJ, Isaacs A, Yazdanpanah M, Arias-Vazquez A, Stricker BH, et al. Polymorphisms of the renin–angiotensin system are associated with blood pressure, atherosclerosis and cerebral white matter pathology. J Neurol Neurosurg Psychiatry. 2007;78(10):1083–1087
  23. Sole X, Guino E, Valls J, Iniesta R, Moreno V. SNPStats: a web tool for the analysis of association studies. Bioinformatics. 2006;22:1928–1929
  24. Gonzalez JR, Armengol L, Sole X, Guinó E, Mercader JM, Estivill X, et al. SNPassoc: An R package to perform whole genome association studies. Bioinformatics. 2007;23(5):644–645
  25. Akasaka H, Katsuya T, Saitoh S, Sugimto K, Fu Y, Takagi S, et al. Effects of angiotensin II type 1 receptor gene polymorphism on insulin resistance in Japanese general population: the Tanno–Sobetsu study. Hypertens Res. 2006;29:961–967
  26. Abdollahi MR, Gaunt TR, Synddall HE, Cooper C, Phillips DI, Ye S, et al. Angiotensin II type 1 receptor gene polymorphism: anthropometric and metabolic traits. J Med Genet. 2005;42:396–401
  27. World Health Organization . Obesity: preventing and managing the global epidemic. Report of a WHO consultation. WHO Technical Report Series No. 894.. Geneva: WHO; 2000;
  28. Leander K, Wiman B, Hallqvist J, Andersson T, Ahlbom A, de Faire U. Primary risk factors of recurrent myocardial infarction/death from coronary heart disease: results from the Stockholm Heart Epidemiology program (SHEEP). Eur J Cardiovasc Prev Rehabil. 2007;14(4):532–537
  29. Takeno M, Yasuda S, Otsuka Y, Morii I, Kawamura A, Yano K, et al. Impact of metabolic syndrome on the long term survival of patients with acute myocardial infarction: potential association with C-reactive protein. Circ J. 2008;72(3):415–419

PII: S1054-8807(10)00049-9

doi: 10.1016/j.carpath.2010.04.002

Cardiovascular Pathology
Volume 20, Issue 3 , Pages 156-161 , May 2011