Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress

Pyle, Amy L.; Li, Bin; Maupin, Amanda B.; Guzman, Raul J.; Crimmins, Dan L.; Olson, Sandy; Atkinson, James B.; Young, Pampee P.

doi:10.1016/j.carpath.2008.12.006

« Previous Next »Cardiovascular Pathology
Volume 19, Issue 2 , Pages e13-e20, March 2010

Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress

Amy L. Pyle
- Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA
Bin Li
- Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA
Amanda B. Maupin
- Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA
Raul J. Guzman
- Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA
- Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN, USA
Dan L. Crimmins
- Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA
Sandy Olson
- Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA
James B. Atkinson
- Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA
Pampee P. Young
- Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA
- Department of Internal Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
- Department of Veterans Affairs, Vanderbilt University Medical Center, Nashville, TN, USA
- Corresponding author. Department of Pathology, Vanderbilt University School of Medicine, 1161 21st Ave. South, CC3321a MCN, Nashville, TN 37232, USA. Tel.: +1 615 936 1098; fax: +1 615 343 7023.

Received 16 April 2008; received in revised form 11 December 2008; accepted 19 December 2008. published online 12 February 2009.

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Grants: This work was supported by the National Institutes of Health Training Grant 5T32HL07751 (ALP), Vanderbilt Physician Development Award, Veterans Affairs Career Development Award, and KO8HL84020 from the National Institutes of Health, Bethesda, Maryland (PPY).

Disclosures: This work was also supported by the Pfizer Atorvastatin Research Award (PPY).

PII: S1054-8807(08)00187-7

doi:10.1016/j.carpath.2008.12.006

Published by Elsevier Inc.

« Previous Next »Cardiovascular Pathology
Volume 19, Issue 2 , Pages e13-e20, March 2010

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