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Fibroblast growth factor-2 promotes in vitro heart valve interstitial cell repair through the Akt1 pathway
09 January 2012
Li Han, Avrum I. Gotlieb
Abstract: Background: Fibroblast growth factor-2 promotes in vitro heart valve interstitial cell repair. Fibroblast growth factor-2 acts through betaglycan which is known to bind both transforming gro...
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The pathophysiology of heart failure
09 January 2012
Clinton D. Kemp, John V. Conte
Abstract: Heart failure is a clinical syndrome that results when the heart is unable to provide sufficient blood flow to meet metabolic requirements or accommodate systemic venous return. This common ...
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Unicommissural aortic valves: gross, histological, and immunohistochemical analysis of 52 cases (1978-2008)
29 December 2011
Michael E. Fealey, William D. Edwards, Dylan V. Miller, Joseph J. Maleszewski
Abstract: Background: Unicommissural aortic valves (UAVs) are rare anomalies in which adjacent cusps of two commissures are congenitally fused. Currently, features of UAVs are poorly characterized. Me...
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Intracardiac thrombi in extracardiac disorders: an autopsy study
26 December 2011
Pradeep Vaideeswar, Smita Divate, Megha Harke
Abstract: Introduction: Intracardiac thrombi (ICT), more commonly encountered at autopsy, are well documented with underlying cardiovascular disease. Occurrence of ICT in systemic diseases without an ...
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Stereological characterization of left ventricular cardiomyocytes, capillaries, and innervation in the nondiabetic, obese mouse
26 December 2011
Carina Gruber, Karin Kohlstedt, Annemarieke E. Loot, Ingrid Fleming, Wolfgang Kummer, Christian Mühlfeld
Abstract: Background: Obesity is associated with left ventricular hypertrophy and dysfunction, but little is known about the structural remodeling of cardiomyocytes, capillaries, and nerve fibers in t...
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